Can you help me to understand the bruising associated with EDS? Print E-mail

Can you help me to understand the bruising associated with EDS? 

Subcutaneous bleeding are caused by collagen abnormalities in the vessel wall. The high frequency of a bleeding tendency in Ehlers-Danlos patients with normal tests for haemostasis (83%) supports the conventional explanation for this clinical feature, that defects in the structural integrity of skin and blood vessels lead to easy bruising. (Anstey A, Mayne K, Winter M, Van de Pette J, Pope FM. "Platelet and coagulation studies in Ehlers-Danlos syndrome." Br J Dermatol. 1991 Aug;125(2):155-63). Disorders of Vascular Fragility - Reed E. Pyeritz MD, PhD Vol 29; (6): 2001
www.physportsmed.com/issues/2001/06_01/pyeritz.htm
Pepin M, Schwarze U, Superti-Furga A, Byers PH. Clinical and genetic features of Ehlers-Danlos syndrome type IV, the Vascular Type. N Engl J Med. 2000 Mar; 342(10):673-80. Erratum in: N Engl J Med 2001 Feb 1;344(5):392
 

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