Hypermobility Type: Hereditary Patterns
Hypermobility Type EDS is inherited in an autosomal
dominant manner. In most cases, the causes of this type of
Ehlers-Danlos Syndrome is unknown.
Mutations in one copy of the TNXB gene may be
responsible for this condition in some people. The TNXB gene makes a
protein called tenascin-X, which functions outside of cells and appears
to interact with other proteins (such as collagen). It is not yet clear
how mutations in this gene lead to clinical features of this disorder.