There are numerous dental problems that may occur; cross-bite, narrow palate, cysts, peg, discolored teeth, jaw pain and clicking, periodontal, and many need braces (i.e orthodontics). There was a study on the prevalence of oral problems reported among a large group of adults with Ehlers-Danlos Syndrome (EDS). In the EDS group those who had daily pain in the masticatory muscles. There was a suggesting that a decline in psychological well-being was also more common in the EDS group. It is important that dental practitioners should be aware of the oral problems associated with EDS and the impact the disease has on quality of life.(Hagberg C .et.al "Ehlers-Danlos Syndrome (EDS) focusing on oral symptoms: a questionnaire study" Orthod Craniofac Res. 2004 Aug;7(3):178-85).

Ehlers-Danlos syndrome (EDS) designates a heterogeneous group of connective tissue disorders characterized by skin elasticity, tissue fragility, and chronic joint pain. Dental findings have been reported with some types of EDS. This case report describes the periodontal findings in a patient with a previously undiagnosed EDS type VIII. Periodontal involvement may lead to the diagnosis of an underlying systemic condition. Identification of suspected etiological factors of periodontal disease may prove critical for the general well-being of some patients.(Perez LA et.al "Treatment of periodontal disease in a patient with Ehlers-Danlos syndrome. A case report and literature review"J Periodontol. 2002 May;73(5):564-70.