Are headaches and migraine related to Ehlers-Danlos Syndrome?
Chronic recurrent headaches may constitute the
neurologic presentation of EDS in the absence of structural,
congenital, or acquired CNS lesions that correlate with their symptoms.
Individuals with EDS may be prone to migraine due to an inherent
disorder of cerebrovascular reactivity or cortical excitability.
Additional studies are needed to elucidate the pathogenesis of
headaches in EDS.(De Jacome "Headache in EDS" Cephalalgia 1999 Nov; 19 (9): 791)